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Product Name:Fmoc-Val-Cit-PAB-PNP CAS#863971-53-3

Fmoc-Val-Cit-PAB-PNP can be used to design cleavable ADC linkers.
It is a peptide compound composed of the Fmoc-Protecting group and two amino acid residues Valine(Val) and Citrulline(Cit) and p-aminobenzoic acid(PAB). PNP represents the p-phenyl group.
The Val-Cit is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma.
The Fmoc is a Protecting group that can protect the N-terminal of the peptide chain, it can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.

A few grams in stock with purity not less than 95%!  

CAS Number: 159858-22-7
Product Name: [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate
Formula: C40H42N6O10
MW: 766.8
Appearance: White to off-white powder
Purity: not less  than 98%
Storage Conditions:  Keep in a dark and cool dry place(-5 to 8 °C)  in closed vessels.
Shipping Conditions: Ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during standard shipping and time spent in Customs.
MOQ: 5 grams,10 grams, 25 gram,s or more
Package In alu foil bag or in Brown vial or HDPE plastic bottle
Production Capacity: Kilograms Scale, bulk order
Availability: More than 100 grams in stock
Report: HNMR and CoA

Known Application

his polypeptide chain(Fmoc-Val-Cit-PAB-PNP CAS#863971-53-3) has certain development value in the field of drug research, as it can bind specifically to some receptors, enzymes, and other molecules, thereby playing a specific biological function. This compound can be used as an agonist, inhibitor, or other specific bioactive molecule to further investigate specific biological processes. In addition, it can also be used in the field of drug research and development, such as designing and developing drugs for specific diseases, such as cancer, cardiovascular disease, and inflammation.

 

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